IndraLab

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USP2 activates Proteasome. 2 / 2

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"At the molecular level, the simplest explanation for this result is that USP2 drives the Ub K48 -Imd molecules to the proteasome and/or ensures the removal of Ub K48 from Imd at the level of the proteasome, then allowing for Imd degradation by the proteasome machinery."

25027767

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reach

"USP2 directly interacts with cyclin D1 to perform deubiquitylation and thereby antagonize proteasome-dependent degradation of cyclin D1."

32006569

INDRA sources:

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IndraLab

Statements

USP2 activates Proteasome. 2 / 2

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