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"Differential regulation of gene expression, as well as loss of USP22 expression, was also demonstrated by independent qRT-PCR of the USP22-dependent upregulated genes TGFB1, SLFN5, TGM2, and DDX60, as well as downregulation of USP22, CXCR4, and AK4 (Fig. 1C), confirming the quality of the microarray."