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OTUB1 deubiquitinates ESR1. 4 / 4
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No evidence text available

"OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.|We show that OTUB1 negatively regulates transcription mediated by ERalpha in transient reporter gene assays and transcription mediated by endogenous ERalpha in Ishikawa endometrial cancer cells."

reach
"OTUB1 deubiquitinates ERalpha in vitro and in vivo and stabilizes ERalpha in the nucleus [XREF_BIBR]."

reach
"OTUB1 deubiquitinates estrogen receptor α (ERα) and negatively regulates ERα mediated transcription ( Stanisic et al., 2009 )."