IndraLab

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P5091 activates Mice. 3 / 3
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"32 Our study here aimed to examine the effect of P5091 on antitumor immunity and its possible role in cancer immunotherapy.In our study, we found that P5091 promoted colon cancer cell apoptosis and death in CT26 xenografted mice and that the effect was similar when compared to an anti-PD-1-treated group."
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"In vivo, P5091 effectively attenuates bone loss in OVX mice."
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"Furthermore, P5091 treatment caused FOXP3 loss in Treg cells decreased the proportion of Treg cells in tumor bearing mice."
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