IndraLab

Statements

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"Furthermore, inhibition of USP9x in vivo suppressed obesity induced breast cancer metastasis."
28115363
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"The results indicated that FA-M (PTX) prevented pulmonary metastasis of H22, and the efficacy was stronger than pure PTX and simple PTX conjugated micelles."
24790440
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"Noting that USP9X suppresses the metastasis of PDAC but promotes GEM resistance, it is easy to speculate that USP9X might recognize and mediate diverse substrates which hold the same domain, thereby inducing various functions."
38174069
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"Consistent with the functions in vitro and in bulk cell population (Fig. 5A–C and Fig. 2E), within both in vivo imaging and anatomical assays, USP9X deprivation suppressed the tumor regeneration and intraperitoneal metastasis capability of CSCs."
40246814
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"The depletion and pharmacological inhibition of USP9X by WP1130, an inhibitor of USP9X, downregulate endogenous Snail1 protein, inhibit cell migration, invasion, metastasis, and increase cellular sensitivity to cisplatin and paclitaxel both in vitro and in vivo, whereas the reconstitution of Snail1 in cells with USP9X depletion at least partially reverses these phenotypes."
35506169
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"USP9X inhibits metastasis in pulmonary sarcomatoid carcinoma by regulating epithelial-mesenchymal transition, angiogenesis and immune infiltration."
38964032