
IndraLab
Statements
Pyrrolidine dithiocarbamate inhibits RELA. 5 / 5
4
|
1
reach
"Compared to the group with palmitate treatment alone, pyrrolidine dithiocarbamic acid (10/20 micromol/L) significantly inhibited the palmitate induced increase of p-NF-kappaB p65 (1.39 +/- 0.12, 1.25 +/- 0.10 vs 1.76 +/- 0.14, both P < 0.05), restored the palmitate induced decrease of caspase-3 (2.24 +/- 0.28 vs 1.29 +/- 0.27, P < 0.05) and inhibited the palmitate induced increase of cleaved caspase-3 (0.63 +/- 0.01 vs 1.13 +/- 0.10, P < 0.05)."