IndraLab

Statements

RIGI activates CYLD. 2 / 3
| 2
reach
"Based on the in vitro assessments, this miRNA directly targets cylindromatosis (CYLD) (a negative regulator of antiviral responses through removing lysine (K)-63-linked polyubiquitin of RIG-I), increases RIG-I ubiquitination and thereupon production of IFNs-I [109].7 hsa-miRNAs and SARS-CoV-2-induced interfering factors."
| PMC
reach
"The data indicate that CYLD targets RIG-I as well as TBK1 for deubiquitination that leads to inactivation of the signaling."
18703349