IndraLab

Statements


DDX58 activates CYLD. 2 / 3
| 2

reach
"The data indicate that CYLD targets RIG-I as well as TBK1 for deubiquitination that leads to inactivation of the signaling."

reach
"Based on the in vitro assessments, this miRNA directly targets cylindromatosis (CYLD) (a negative regulator of antiviral responses through removing lysine (K)-63-linked polyubiquitin of RIG-I), increases RIG-I ubiquitination and thereupon production of IFNs-I [109].7 hsa-miRNAs and SARS-CoV-2-induced interfering factors."
| PMC