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Daidzein decreases the amount of USP19. 6 / 6
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"Daidzein repressed USP19 expression at the mRNA and protein levels when C2C12 myotubes were cultured in the presence of daidzein ( Fig. 1 B)."
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"Dietary daidzein decreased the expression of USP19 at the mRNA and protein levels in soleus muscle of female mice only ( Fig. 2 B and C)."
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"These results indicate that in soleus muscle of OVX mice, daidzein inhibits the E2-dependent increase in USP19 expression through ERβ and the E2-depdentnt decrease in muscle ratio.To determine the eff[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Thus, these results indicate that daidzein increases ERβ recruitment to the Usp19 hERE and down-regulates USP19 expression by inhibiting E2-dependent recruitment of ERα."
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"The contributing ratios of daidzein and its metabolites for skeletal muscle health will be an interesting avenue for future work.In the present study, we provide evidence that the ERβ agonist daidzein[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We demonstrate that dietary daidzein down-regulates USP19 expression and increases soleus muscle mass in young female mice.All animals in the present study were cared for in accordance with the guidel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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