IndraLab

Statements

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"Benzyl isothiocyanate attenuates activation of the NLRP3 inflammasome in Kupffer cells and improves diet-induced steatohepatitis."
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"In contrast, the use of benzyl isothiocyanate reduced lipopolysaccharide and cholesterol crystal-induced activation of NLRP3 inflammatory vesicles in Kupper cells and prevented the development of MASH (Chen et al., 2020)."
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"Further studies with different disease models can be helpful to understand which pathways or downstream molecules are involved in the inhibition of NLRP3 inflammasome by BITC ( Chen et al., 2020 )."
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"Next, we examined whether BITC suppresses LPS/CC-induced activation of NLRP3 inflammasome in Kupffer cells."
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