IndraLab

Statements


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"Given the demonstrated anti-inflammatory effects of endocannabinoids, the present study was designed to test whether anandamide (AEA) or its metabolites diminish NLRP3 inflammasome activation and prevent podocyte injury and associated glomerular damage during hyperhomocysteinemia (hHcys)."

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"Given the demonstrated anti-inflammatory effects of endocannabinoids, the present study was designed to test whether anandamide (AEA) or its metabolites diminish NLRP3 inflammasome activation and prevent podocyte injury and associated glomerular damage during hyperhomocysteinemia (hHcys)."

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"Treatment with AEA, on the other hand, has sharply reduced both IL-18 and its activator, caspase-1, to match the findings of Li et al. , who showed that AEA inhibited the NLRP3 inflammasome and its downstream axis caspase-1/IL-18."