IndraLab

Statements


USP47 increases the amount of CDC25A. 3 / 3
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"To verify this, we performed a quantitative real-time PCR and we found that USP47 but not beta-Trcp depletion increases Cdc25A mRNA levels (XREF_FIG)."

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"Although we have not elucidated yet the precise mechanism through which USP47 depletion causes Cdc25A upregulation, our results suggest that USP47 could potentially regulate Cdc25A expression at a transcriptional level."

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"Collectively, these results showed that USP47 potentially regulates Cdc25A expression at mRNA level, suggesting that USP47 does not regulate beta-Trcp activity."