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USP27X deubiquitinates HES1. 2 / 2

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"Knockdown of Usp22 shortened the half-life of Hes1, delayed its oscillation, and enhanced neuronal differentiation in mouse developing brain, whereas mis-expression of Usp27x reduced neuronal differentiation."

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"In addition, USP27 could regulate neuronal differentiation of stem cells in the developing mouse neocortex by deubiquitinating and stabilizing Hes1 [22]."

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IndraLab

Statements

USP27X deubiquitinates HES1. 2 / 2

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