IndraLab

Statements


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"Caffeine is known to downregulate STAT-1 signaling with potential anti-inflammatory effects in RA."

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"Caffeine is known to downregulate STAT-1 signaling with potential anti-inflammatory effects in RA.37 Theophylline also has anti-inflammatory properties in rats and systemic inflammation may reduce its concentration.38 ."

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"Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity."

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"Upstream regulator analysis suggests that caffeine inhibits STAT1 signaling, which was confirmed by showing reduced phosphorylated STAT1 after caffeine treatment."