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Tsh activates KCNQ1. 2 / 2

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"We detected endogenously expressed KCNQ1 and KCNE2 proteins, which appeared to be upregulated by TSH or its major downstream effector, cAMP, in FRTL5 cell membrane fractions (XREF_FIG)."

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"This hypothesis is supported by the observation that the function of the TSH-stimulated KCNQ1/KCNE2 potassium channel is required for thyroid hormonogenesis by sustaining normal NIS-mediated iodide transport in the thyroid follicular cell [40]."

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Tsh activates KCNQ1. 2 / 2

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