IndraLab

Statements

OTUB1 binds HMGCS1. 3 / 3
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sparser
"Importantly, MAT2A expression enhanced the interaction between OTUB1 and HMGCS1 (Fig.  xref ), resulting in reduced OTUB1-dependent ubiquitination of HMGCS1 (Fig.  xref )."
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sparser
"In contrast, endogenous knockdown of MAT2A resulted in decreased binding of OTUB1 to HMGCS1 (Fig.  xref ), accompanied by increased HMGCS1 ubiquitination (Fig.  xref )."
41298385
sparser
"In summary, our findings indicate that MAT2A enhances the binding of OTUB1 to HMGCS1, thereby reducing HMGCS1 ubiquitination levels and improving its stability."
41298385