IndraLab

Statements

CYLD inhibits Neoplasms. 4 / 6
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"This cluster also displays losses on chromosome 16, including the tumor suppressors CYLD and TSC2, and the DNA repair gene PALB2, as well as reduced expression of all three."
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"Regarding TC, with more aggressive behavior, several tumor suppressors including CYLD, CBFB, CDH1, CDH11, CTCF, and ZFHX3 was found, as well as a higher Tumor Mutational Burden (TMB) compared to thymomas (22)."
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"Thus , the up-regulation of CYLD activity is associated with neurodegenerative diseases , whereas the down-regulation of CYLD causes cancers ."
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"CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3."
35131382