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JAK2 activates KCNA3. 3 / 4
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"As a result, KCNA3 channel activity and protein abundance were up-regulated by coexpression of JAK2 or (V617F) JAK2 but not (K882E) JAK2."
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"Coexpression of JAK2 along the KCNA3 in X. laevis oocytes increases the Kv1.3 currents, but they do not possess a tail upon to −100 mV( Hosseinzadeh et al., 2015 )."
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"These results demonstrate that Kv1.3 serves as a crucial signal transducing protein in ox-LDL-induced VSMC proliferation, and that JAK2/STAT3 might mediate Kv1.3 activity in VSMCs.The Kv1.3 potassium [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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