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USP7 decreases the amount of FOXP3. 2 / 2

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"USP7 is upregulated in Treg cells, and the ectopic expression of USP7 decreases Foxp3 polyubiquitylation and increases Foxp3 expression."

31681337

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"The knockdown of USP7 decreased the levels of endogenous FOXP3 and diminished the Treg suppressive activity while ectopic expression of USP7 increased FOXP3 expression by preventing its degradation."

33614551

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IndraLab

Statements

USP7 decreases the amount of FOXP3. 2 / 2

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