Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 increases the amount of IL2. 2 / 2

| 2

➶

reach

"In response to T cell receptor engagement, USP18 deficient T cells exhibit hyperactivation of NF-kappaB and NFAT and produce increased levels of IL-2 compared with the wild-type controls."

23825189

➶

reach

"In our experiments, we found that USP18 deficient naive CD4 + T cells produced increased amounts of IL-2 compared with the WT counterparts stimulated with anti-CD3 and CD28 or under Th17 polarizing conditions."

23825189

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...