IndraLab

Statements


RAD51 activates COPS5. 2 / 2
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"Transiently transfected Rad51 plasmid DNA into Jab1 knockdown cells altered their survival curves; the colony formation in these cells showed a similar pattern with si-Control cells, indicating that ectopic expression in Rad51 can rescue cell repair function in Jab1 deficient cells."

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"These results demonstrated that p53 increases its association with Rad51 promoter in Jab1 knockdown cells, suggesting a major mechanism for reduction of Rad51 protein levels after loss of Jab1."