IndraLab

Statements

HIF hydroxylates OTUB1 on N22. 4 / 4
| 4
sparser
"Following our previous observations of FIH-dependent hydroxylation of OTUB1 on N22 [ xref , xref ], we here investigated the interplay between FIH and OTUB1 in more detail by immunoprecipitation (IP) of endogenous FIH."
31299612
sparser
"In addition, the formation of this complex is dependent on the hydroxylation of OTUB1 on N22 by FIH and sensitive to hypoxia (Fig. xref ), in agreement with the previous report [ xref , xref ]."
35732631
sparser
"OTUB1 Is Hydroxylated on N22 by Endogenous FIH."
26752685
sparser
"These data are consistent with our hypothesis that FIH-dependent N22 hydroxylation of OTUB1 contributes to the regulation of cellular metabolism by FIH."
26752685