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USP33 activates DUSP1. 2 / 2

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"Therefore, USP33 overexpression in prostate cancer may contribute to docetaxel resistance by inhibiting the degradation of its partner DUSP1, leading to impaired JNK activation and apoptosis."

31857702

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"Furthermore, we found that USP33 could interact with the phosphatase DUSP1 to negatively regulate the activation of JNK, while USP33 knockdown promoted the proteasomal degradation of DUSP1."

31857702

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IndraLab

Statements

USP33 activates DUSP1. 2 / 2

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