IndraLab

Statements


KCNA5 activates CASP3. 3 / 5
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"Overexpression of the human KCNA5 gene increases K+ currents (i.e., K+ efflux or loss), accelerates apoptotic volume decrease (AVD), increases caspase-3 activity, and induces apoptosis."

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"Furthermore, studies have demonstrated that KCNA5 gene transfer, in addition to increasing K currents, increased caspase-3 activity and accelerated apoptosis."

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"It has been reported that overexpression of the KCNA5 gene induces accelerated K efflux and increases caspase-3 proteolytic activity, promoting apoptosis [XREF_BIBR]."