IndraLab

Statements

reach
"Ablating UCHL3 significantly attenuates farrerol-mediated stimulation in HR and SCNT embryo development."
37012254
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"Furthermore, UCHL3 was recently suggested to facilitate HR by deubiquitylating RAD51 in a DSB-dependent manner via phosphorylation on the same site that we identified (S75) , however, we did not observe any defects in HR caused by UCHL3 depletion, nor did we detect any interaction with RAD51 in our mass spectrometry analyses."
30559450
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"Our results also suggest that UCHL3 deficiency causes HR defect but does not affect cell proliferation (Fig. 1D; Supplemental Fig. S1A)."
27941124