"We previously demonstrated that c-Src directly associates with EGFR upon EGF stimulation and c-Src activation contributes to HNSCC cell invasion ( xref )."
"This mechanism involves the EGF-dependent association of c-Src with HER1 and phosphorylation of the receptor by c-Src on residues Tyr 845 and Tyr 1101."
"We have previously reported that c-Src directly associates with EGFR in HNSCC cells upon EGF stimulation ( xref )."
"EGFR and Src interaction with EGF stimulation were also analyzed by the same method ( xref )."
"Furthermore, it has been reported that Src directly associates with the epidermal growth factor receptor (EGFR) in OSCC cells upon stimulation with EGF and phosphorylates Crk-associated substrate (Cas), podoplanin acting downstream of Src and Cas to promote cell migration."
"In experimental systems this synergistic growth requires EGF-dependent association of c-Src with the EGFR and phosphorylation of Tyr-845 of the receptor by c-Src."
"Significantly, both herbimycin A and PP2 abrogated ouabain-induced but not epidermal growth factor-induced Src binding to the EGFR and the subsequent EGFR tyrosine phosphorylation."
"We have previously demonstrated that c-Src directly associates with EGFR upon EGF stimulation in HNSCC cells ( xref )."