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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EGF binds EGFR and PTPD1. 2 / 2

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"Dynamic PTPD1/EGFR-containing signalling complexes are formed even before EGF stimulation as demonstrated by fluorescence cross-correlation spectroscopy (FCCS)."

25062045

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"Although, steady state distribution of PTPD1 to actin filaments and adhesion plaques has been previously observed in primary fibroblasts xref , our data show that in cancer cells that over expressed PTPD1, EGFR/PTPD1-containing signalling complexes could be formed at membrane ruffles before EGF stimulation ( xref )."

25062045

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...