IndraLab

Statements

TIMP1 binds CD44. 3 / 3
| 2 1
sparser
"Interestingly, CD44 also correlates with increased aggressiveness and resistance to radiation therapy and chemotherapeutics (reviewed in xref ) and TIMP-1 binding of the proMMP-9/CD44 complex has been shown to mediate cell survival through Akt activation xref ."
22957045
reach
"Previous studies have demonstrated that TIMP-1 binds a proMMP9 and CD44 complex that facilitates erythroid cell survival and is localized to the cell surface [XREF_BIBR]."
28030805
reach
"It is tempting to hypothesize that in agreement with the observations by others MMP-9 or MMP9/TIMP-1 binding to cellular CD44 affects the CD44 signaling [85]."
22438979