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Ginsenoside Rg1 inhibits CASP1. 3 / 3
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"In the present study, we found that Rg1 treatment significantly reversed the cerebral I/R-induced increase of IL-1β, caspase-1, ASC and NLRP1."
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"Similarly, the q-PCR findings also indicated that Tempol and Rg1 (5, 10, and 20 mg/kg) effectively reversed the up-regulation of NLRP3 and Caspase-1 mRNA in the liver of mice induced by LPS ( Fig. 6 H[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Rg1 markedly reduced the symptoms and disease biomarkers in mice with ovalbumin-induced allergic rhinitis and also inhibited caspase-1 activation in the nasal mucosa tissue ."
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