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"To identify the E3 ubiquitin ligase that mediates BaP induced ACE2 degradation, the expression of several critical E3 ligases, e.g., the F-box (40 amino acid motif)-containing E3 ligase S-phase kinase associated protein 2 (Skp2), beta-transducin repeat containing E3 ubiquitin protein ligase (beta-TRCP), the nuclear interaction partner of ALK (NIPA), the RING finger and WD repeat domain 3 (RFWD3), and deubiquitinase ubiquitin specific protease 10 (USP10) were tested in cells treated with BaP."
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