IndraLab

Statements



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"Effects of hERG potassium channel protein on the biological behavior of the tumor that can inhibit the growth of tumor cells by inhibiting the expression or channel current of IhERG and promote tumor cell differentiation or apoptosis, reduce its invasiveness."

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"Kv11.1 activation-dependent Cav-1 dephosphorylation induced with NS1643 also reduced cell migration and invasion, consistent with its ability to regulate focal adhesion dynamics."

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"Knockdown of hERG1 significantly suppressed cellular proliferation and invasion, and induced apoptosis, while inhibition of hERG1 significantly decreased activation of NF-kappaB."

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"XREF_FIG - XREF_FIG, hERG1 downregulation and/or inhibition prevented proliferation and invasion, and induced apoptosis of osteosarcoma cells."

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"[Downregulation of Herg1 suppresses osteosarcoma proliferation and invasion by targeting Hippo signaling pathway]."