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USP46 increases the amount of PHLPP1. 2 / 2

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"To determine if the interaction of PHLPP and USP46 is required for USP46 mediated increase of PHLPP expression, the full-length PHLPP1 or the USP46 binding deficient Delta1139 mutant was co-expressed with USP46."

22391563

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"Knockdown of USP46 in HCT116 cells has been observed to decrease the levels of PHLPP isoforms and, consequently, contribute to hypoxia-induced drug resistance in CRC[83]."

38292842

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USP46 increases the amount of PHLPP1. 2 / 2

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