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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Phosphorylated EGFR binds GRB2 and SH2 domain. 1 / 1

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reach

"This begins with the recruitment of Grb2, which contains an SH2 domain and can bind either directly to the phosphorylated EGFR, or to Shc, an adapter protein that becomes associated with and tyrosine phosphorylated by the EGFR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...