IndraLab

Statements

GRB2 binds phosphorylated EGFR and SH2 domain. 2 / 2
| 2
reach
"This begins with the recruitment of Grb2, which contains an SH2 domain and can bind either directly to the phosphorylated EGFR, or to Shc, an adapter protein that becomes associated with and tyrosine phosphorylated by the EGFR."
18949068
reach
"c-Cbl is recruited to activated EGFR either by directly binding to their TKB domain at the phosphotyrosine residue 1045 in EGFR [15] or by an indirect mechanism mediated by Grb2 – the SH3 domains of G[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
18400375