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UCHL3 binds FlaG. 6 / 6
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"These data were in line with observed c-NHEJ activities being reduced in UCHL3 KO#2 cells, which was largely rescued by exogenously expressed FLAG-UCHL3 (Fig.  xref )."
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"Western blot analyses revealed that HA-CTNNB1 expression gradually increased with the increased expression of FLAG-UCHL3, and this increase was dose dependent (Fig.  xref D)."
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"Our results demonstrate that there was an interaction between FLAG-UCH-L3 and GFP-β-catenin; however, we did not observe this interaction in cells transfected with the inactive mutant of UCH-L3 (UCH-L3 C95S) ( xref )."
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"To evaluate the effect of UCHL3 DUB activity on CTNNB1 stability, we overexpressed FLAG-UCHL3 or the FLAG-UCHL3 C94A mutant and found that the stability of FLAG-UCHL3 binding to HA-CTNNB1 depended on its ubiquitinase activity (Fig.  xref E)."
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"We observed that FLAG-BAP1 ( xref B, upper panel), but not FLAG-UCHL3 ( xref B, lower panel), directly binds to HA-KEAP1."
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"As shown in Fig.  xref G, the protein half-life of HA-CTNNB1 was obviously extended in the presence of FLAG-UCHL3 compared to that observed when an empty vector was used."
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