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USP21 activates Neoplasms. 3 / 4
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"USP16 was then found to promote K-RAS-mediated lung tumors, and knockout of USP16 in mice attenuates lung tumorigenesis induced by K-ras mutation."
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"USP21 promotes cell proliferation , tumor progression , and colony formation , and enhances cancer stem cell self-renewal ."
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"More so, modulation of USP16 in CD19 and GD2 CAR-expressing T cells seemed to potentiate the self-renewal abilities and functional efficiency in hindering tumor growth in two leukemia and neuroblastom[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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