IndraLab

Statements

Chloroquine inhibits STING1. 4 / 4
| 4
reach
"Brefeldin A, but not chloroquine, blocked STING trafficking, indicating that STING locates from the ER via the Golgi to vesicles in the perinuclear region (XREF_SUPPLEMENTARY)."
19776740
reach
"Chloroquine, which inhibits the lysosomal degradation pathway, could only partially block the degradation of MITA [72], suggesting MITA is mostly degraded by a non-lysosomal degradation pathway."
24929887
reach
"Degradation of STING occurred in the lysosomal compartment since chloroquine, which inhibits lysosomal degradation, prevented STING degradation (XREF_SUPPLEMENTARY)."
24119841
reach
"Chloroquine, a lysosomal inhibitor which reportedly prevents STING degradation, did not block STING trafficking, confirming that STING degradation occurs after translocation (XREF_FIG)."
28763789