IndraLab

Statements

USP34 activates AXIN. 3 / 3
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"In colon carcinoma cell lines that show activation of Wnt and beta-catenin signaling downstream of the DC, Axin and USP34 were found to positively regulate beta-catenin-dependent transcription [XREF_BIBR] whereby USP34 supported the nuclear accumulation of Axin [XREF_BIBR]."
24975604
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"Recent studies have found that USP34 is a component of the Axin complex, and directly regulates the β-catenin destruction complex by mediating Axin stability [20] ."
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"For example, USP34 increases the stability of Axin, thereby promoting its nuclear accumulation (Lui et al., 2011)."
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