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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP34 activates AXIN. 2 / 2

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"In colon carcinoma cell lines that show activation of Wnt and beta-catenin signaling downstream of the DC, Axin and USP34 were found to positively regulate beta-catenin-dependent transcription [XREF_BIBR] whereby USP34 supported the nuclear accumulation of Axin [XREF_BIBR]."

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"For example, USP34 increases the stability of Axin, thereby promoting its nuclear accumulation (Lui et al., 2011)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...