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ZUP1 binds Ubiquitin. 2 / 2

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"We surmised that this configuration might impart preferential binding of ZUFSP to Ub chains, as reported for other tandem UBDs ( Husnjak and Dikic, 2012; Sims and Cohen, 2009 )."

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reach

"Pull-down experiments in lysate using Ub-, SUMO2-, or UFM1 conjugated agarose revealed that FLAG-ZUFSP and FLAG-ZUFSP (298-578) interacted with Ub-agarose, but not with UFM1- or SUMO2-agarose, suggesting that ZUFSP binds preferentially to Ub."

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IndraLab

Statements

ZUP1 binds Ubiquitin. 2 / 2

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