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Halothane inhibits KCNH2. 3 / 3
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"Halothane inhibits HERG currents expressed in oocytes in a concentration dependent manner."
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"The authors ' results demonstrate that halothane decreased HERG currents by modulating kinetic properties of HERG channels, decreasing their open probability."
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"On the other hand, in vitro electrophysiological studies have shown that some anesthetics including halothane and pentobarbital can significantly suppress the HERG channels ( Bachmann et al., 2002; Li[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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