IndraLab

Statements

Lithium(1+) inhibits IFNB1. 3 / 3
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"Lithium attenuates IFN-beta production and antiviral response via inhibition of TANK binding kinase 1 kinase activity."
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"Furthermore, lithium significantly reduced the STING agonist DMXAA-activated ifnb1 and inflammatory factors in NPC1 and NPC1 fibroblasts (Figures 3D and S2A)."
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"The ability of the lithium to inhibit IFN-beta production was confirmed in vivo, as mice treated with lithium chloride exhibited decreased levels of IFN-beta upon Sendai virus infection."
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