IndraLab

Statements

USP24 deubiquitinates EP300. 3 / 3
| 3
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"USP24 deubiquitinates and stabilizes the histone acetyltransferase p300, thereby facilitating histone H3 acetylation of the IL-6 promoter and thus IL-6 transcription."
33466790
reach
"Indeed, we observed that USP24 interacts with p300, and knockdown of USP24 increased p300 ubiquitination, and this effect of USP24 knockdown was abolished after treatment with the proteasome inhibitor MG132."
30266897
reach
"The in vitro enzymatic assay using the purified USP24 protein demonstrated that USP24 decreased the p300 ubiquitination signal (XREF_FIG)."
27991932