IndraLab
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"The reduced Akt1 kinase activity observed upon statins treatment, resulted in an increase in dephosphorylation on FoxO3 and FoxO1 transcription factors, their translocation into the nucleus, and activation of the Atrogin1 and MAFbx gene encoding ubiquitin ligase E3, which eliminates MyoD, calcineurin, eIF3-F translation initiator, and FoxO1 [XREF_BIBR]."