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EPHA2 activates USP3. 2 / 2
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"And knockdown of EPHA2 expression reversed the pro-tumour effects of USP3-upregulating."

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"The knockdown of EPHA2 in 143B cells inhibited the activation of the PI3K/AKT signaling pathway and partially reversed the activation of USP3 in this signaling pathway (Fig. 6A)."