IndraLab

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ATXN3 activates PTEN. 2 / 3

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"In contrast, the two individual ATXN3 siRNAs (siATXN3_3 and _ 5) that caused the most profound PTEN induction (XREF_FIG and XREF_FIG) blunted Akt T308 phosphorylation in response to EGF (XREF_FIG)."

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reach

"Therefore, ATXN3 may directly regulate the PTEN transcript, or indirectly affect it through regulation of a ceRNA such as PTENP1."

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IndraLab

Statements

ATXN3 activates PTEN. 2 / 3

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