IndraLab

Statements


OTUD7B leads to the deubiquitination of RIPK1. 2 / 2
1 | 1

reach
"OTUD7B, a newly identified member of the A20 family of DUBs, inhibits RIP1 ubiquitination and downstream IKK activity and NF-kappaB signalling [XREF_BIBR]."

"USP21 and Cezanne or OTUD7B negatively regulate NFκB signaling by deubiquitinating and inactivating RIP1 upon TNF-α?stimulation, providing a feedback loop in the proinflammatory signaling"