IndraLab

Statements

OTUD7B deubiquitinates RIPK1. 3 / 5
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"OTUD7B, a newly identified member of the A20 family of DUBs, inhibits RIP1 ubiquitination and downstream IKK activity and NF-kappaB signalling [XREF_BIBR]."
25595906
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"Also, the A20 family member Cezanne reportedly deubiquitylates RIP1 but seems to function non-redundantly to A20 [81] ."
19217783
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"Similar to A20, Cezanne is recruited to the TNF-RI complex upon TNF stimulation and promotes RIP1 de-ubiquitination, thereby decreasing NF-κB signaling [106] ."
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