IndraLab

Statements

UCHL1 inhibits AKT. 4 / 5
| 4
reach
"These data provide the first in vivo evidence for DUB driven oncogenesis and suggest that UCH-L1 hyperactivity deregulates normal Akt signaling."
20574456
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"Taken together, it appears that UCHL1 suppresses the growth of LNCaP cells via stabilization of tumour suppressor protein such as p53 and by inactivating AKT and PKB pathway."
21999842
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"Our data suggest that PI3K and Akt pathway is possibly involved in apoptosis in breast cancer cells and blocked by UCH-L1."
18949367
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"Taken together, it appears that UCHL1 suppresses the growth of LNCaP cells via stabilization of tumour suppressor protein such as p53 and by inactivating AKT and PKB pathway."
21999842