IndraLab

Statements

Mercury(2+) inhibits NLRP3. 5 / 5
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"In addition, mercury selectively inhibited NLRP3 and non-canonical inflammasome activation.The role of arsenic in innate immune cells has been progressively studied, although T lymphocytes have been more studied than monocytes or macrophages."
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"Taken together, mercury and arsenic inhibited NLRP3 and non-canonical inflammasomes in both human and mouse macrophages."
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"Mercury and arsenic inhibit activation of NLRP3 inflammasome."
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"Mercury and arsenic inhibit non-canonical NLRP3 inflammasome."
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"Taken together, mercury and arsenic inhibited NLRP3 and non-canonical inflammasomes in both human and mouse macrophages.Next, the inhibitory effects of mercury and arsenic on NLRP3 inflammasome activation were assessed in an animal study."
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