IndraLab

Statements

Arsenite(3-) inhibits IKBKB. 4 / 4
1 | 3
reach
"Thiol-reactive arsenite suppresses IKK activation through oxidative modification of a critical cysteine residue, Cys179, in the activation loop of IKKbeta [30]."
12023051
reach
"In the following study to explore the possible upstream protein kinase (such as ATR, CHK1, LKB1, DAPK1) that might be responsible for triggering p53 dependent IKKbeta repression induced by arsenite, we found the significant upregulation of DAPK1 expression and activation of ATR, CHK1 and LKB1 (data not shown) in HepG2 cells after arsenite exposure."
30177839
reach
"Immunocytochemical staining and Western blotting results revealed increased expression of Caveolin-1, IKKbeta, and COX-2 but decreased eNOS in SV-HUC-1 cells treated with low concentration of arsenite."
22824620
ctd
No evidence text available
10967126