IndraLab

Statements

PUM3 activates KCNK2. 6 / 6
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"LP and PUFA activation of TREK and TRAAK channels thus clearly involves different mechanisms."
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"The half-activation of TREK-1 by each PUFA and ML402 are presented in the Table xref ."
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"TREK-1 was not activated by the C18:3 n-3 PUFA and consequently Em did not change (Fig.  xref A)."
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"These results are supported by in vitro data showing the protective role PUFA mediated KCNK2 activation has on primary cultures of neurons during oxygen/glucose deprivation studies ."
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"LP and PUFA activation of TREK and TRAAK channels thus clearly involves different mechanisms."
11454447
sparser
"TREK-1 channel is modulated by intracellular signalling pathways, related to PKA, PKC and PKG signalizations xref – xref , but to the best of our knowledge, no study between PUFA activation of TREK-1 and phosphorylation levels has been performed so far."
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