IndraLab

Statements


AP180 binds CALM1 and Clathrin. 3 / 3
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sparser
"However, both AP180 and CALM S1&2 mutants did not bind clathrin significantly different to the non-specific binding of GST alone, whereas Site 1 alone was significantly different to GST alone for both AP180 ( P < 0.01) and CALM ( P < 0.001)."

sparser
"The above experiments demonstrated that Site 1, in particular, has a large effect on the interaction of clathrin with AP180 or CALM."

sparser
"Despite that AP180 and CALM are highly abundant components in their respective CME roles, there is no similarly detailed mechanism of AP180 or CALM binding to clathrin, as there is with AP2."