IndraLab

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Hypoxia decreases the amount of OTUD6B. 1 / 1
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"Compared with hypoxia group, hypoxia + Calpain-1 knockout group not only improved the pathological changes of PAH, but also significantly reduced the protein expression of Otud6b, suggesting that Calpain-1 plays an important role in the regulation of Otud6b.Calpain is a conservative family of calcium dependent cysteine proteases that are commonly expressed in all cells [16, 17]."